Author/Authors :
Michael R. Angelastro، نويسنده , , Angela L. Marquart، نويسنده , , Philip M. Weintraub، نويسنده , , Cynthia A. Gates، نويسنده , , Marie E. Laughlin، نويسنده , , Thomas R. Blohm، نويسنده , , Norton P. Peet، نويسنده ,
Abstract :
Androstenes bearing a cyclopropyl group attached to the C-17β position with a heteroatom linker, designed as mechanism-based inhibitors of steroid C17(20) lyase, were found to be potent, time-dependent inhibitors of this enzyme.
