3-substituted alanines inactivate γ-aminobutyric acid aminotransferase by the same mechanism as do 4-amino-5-halopentanoic acid analogues

L-Serine O-sulfate inactivates γ-aminobutyric acid aminotransferase (GABA-AT) by a mechanism that involves elimination of the leaving group and an enamine rearrangement, the same mechanism as that for the inactivation of GABA-AT by 4-amino-5-fluoropentanoic acid.