• Title of article

    Irreversible inhibitions of serine proteases by peptidyl allylic halide derivatives

  • Author/Authors

    Tsuyoshi Ohba، نويسنده , , Eitatsu Ikeda، نويسنده , , Jun Wakayama، نويسنده , , Hisashi Takei، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    6
  • From page
    219
  • To page
    224
  • Abstract
    Peptidyl 4-amino-5-phenyl-2-pentenyl bromide (7a, 9a, 10a) and chloride derivatives (7b, 9b, 10b) were found to be active-site directed irreversible inhibitors of α-chymotrypsin but did not show any irreversible inhibitory activity toward porcine pancreatic elastase.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1996
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787888