Title of article :
The effect of fluorine substitution on the antimalarial activity of tebuquine
Author/Authors :
Paul M. OʹNeill، نويسنده , , Shaun R. Hawley، نويسنده , , Richard C. Storr، نويسنده , , Stephen A. Ward، نويسنده , , B. Kevin Park، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
A novel synthetic route has been developed for the synthesis of fluorotebuquine which was active against the chloroquine resistant K1 strain of Plasmodium Falciparum, but less potent than both chloroquine and tebuquine against the 3D7 strain.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters