• Title of article

    A PLE-based resolution of cocaine, pseudococaine, and 6- and 7-methoxylated cocaine analogues

  • Author/Authors

    A. P. Kozikowski، نويسنده , , D. Simoni، نويسنده , , P. G. Baraldi، نويسنده , , I. Lampronti، نويسنده , , S. Manfredini، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    4
  • From page
    441
  • To page
    444
  • Abstract
    The enzymatic hydrolysis of racemic cocaine and cocaine analogues using pig liver esterase (PLE) is shown to afford a practical means for achieving their chemical resolution. This reaction was found to proceed not only with good enantioselectivity, but with an interesting chemoselectivity as well.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1996
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787934

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=787934