Title of article
Mechanism-based inactivation of α-chymotrypsin
Author/Authors
Tsuyoshi Ohba، نويسنده , , Naoki Tsuchiya، نويسنده , , Kuniko Nishimura، نويسنده , , Eitatsu Ikeda، نويسنده , , Jun Wakayama، نويسنده , , Hisashi Takei، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
543
To page
546
Abstract
The peptidyl ester derivatives of 2,2-dichlorocyclopropanol and the amide derivative of 2,2-dichlorocyclopropylamine were prepred as novel mechanism-based inactivators of α-chymotrypsin. The esters inactivated α-chymotrypsin irreversibly but the amide did not show any irreversible inhibitory activity toward α-chymotrypsin.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787954
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