• Title of article

    The antiinfluenza activity of pyrrolo[2,3-d]pyrimidines

  • Author/Authors

    Marcos L. Sznaidman، نويسنده , , Eric A. Meade، نويسنده , , Lilia M. Beauchamp، نويسنده , , Stuart Russell، نويسنده , , Margaret Tisdale، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    4
  • From page
    565
  • To page
    568
  • Abstract
    From a group of pyrrolo[2,3-d]pyrimidine compounds that have been screened against influenza virus, one derivative, 4-(3-piperidinyl benzylamino)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine (9), has shown promising activity against both the A and B strains. The compound had activity comparable to amantadine, but was inactive when given orally. 4-(Substitutedphenyl ethylamino)-2-methyl-7H-pyrrolo[2,3-d]pyrimidines showed no improved activity.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1996
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787958