Title of article
S-nitrosation of proteins by N-methyl-N-nitrosoanilines
Author/Authors
Zhengmao Guo، نويسنده , , Andrea McGill، نويسنده , , Libing Yu، نويسنده , , Jun Li، نويسنده , , Johnny Ramirez، نويسنده , , Peng George Wang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
573
To page
578
Abstract
Substituted N-methyl-N-nitrosoanilines are found to function as stable, potent, nitrosating agents for S-nitrosation and inactivation of cysteine proteases such as papain, bromelain and aldehyde dehydrogenase under physiological conditions in a time and concentration dependent manner. Spectroscopic studies on the reaction products have proved that the mechanism of the inactivation is a S-nitrosation of the protein.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787960
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