Title of article
Thiophenoxy peptides: A new class of HIV replication inhibitors
Author/Authors
Valérie Niddam، نويسنده , , Michel Camplo، نويسنده , , Dung Le Nguyen، نويسنده , , Jean-Claude Chermann، نويسنده , , Jean-Louis Kraus، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
609
To page
614
Abstract
A new series of modified peptides inhibitors of HIV is reported. These peptides utilize the isosteric substitution of a methylene group by a sulfur atom in a phenylalanine residue. Two thiophenoxy peptides 9 and 11 inhibit in vitro HIV-1 replication in MT4 cells with IC50 values of 5 and 10 μM respectively.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787967
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