Title of article
Imino 1,2,3,4-tetrahydrocyclopent[b]indole carbamates as dual inhibitors of acetylcholinesterase and monoamine oxidase
Author/Authors
David M. Fink، نويسنده , , M. G. Palermo، نويسنده , , Gina M. Bores، نويسنده , , Francis P. Huger، نويسنده , , Barbara E. Kurys، نويسنده , , Michael C. Merriman، نويسنده , , Gordon E. Olsen، نويسنده , , Wayne Petko، نويسنده , , Gerard J. OʹMalley، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
625
To page
630
Abstract
A series of imino 1,2,3,4-tetrahydrocyclopent[b]indole carbamates was prepared and evaluated as dual acetylcholinesterase (AChE) and monoamine oxidase (MAO) inhibitors. Halogen substitution ortho to the carbamate functionality in the eight position resulted in a significant increase in binding affinity for both AChE and MAO-A.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787970
Link To Document