Author/Authors :
Fumio Hashimoto، نويسنده , , Yoshiki Kashiwada، نويسنده , , Gen-ichiro Nonaka، نويسنده , , Itsuo Nishioka، نويسنده , , Toshihiro Nohara، نويسنده , , L. Mark Cosentino، نويسنده , , Kuo-Hsiung Lee، نويسنده ,
Abstract :
Thirty-eight tea polyphenols were evaluated for their inhibitory effect against HIV replication in H9 lymphocyte cells. 8-C-Ascorbyl (−)-epigallocatechin (13) and theasinensin-D (32) demonstrated relatively potent anti-HIV activity with EC50 values of 4 and 8 μg/mL and therapeutic indexes of 9.5 and 5, respectively.
