Title of article
Two syntheses of 2S-[2-2H]-kynurenine
Author/Authors
Fiona C. Ross، نويسنده , , Nigel P. Botting، نويسنده , , Paul D. Leeson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
875
To page
878
Abstract
The synthesis of 2S-[2-2H]-kynurenine is described using two different routes. Diacetylation/racemisation of racemic kynurenine in deuterium oxide followed by acylase catalysed resolution is the most direct route. The alternative is to prepare 2S-[2-2H]-tryptophan by a similar procedure and then convert this through to 2S-[2-2H]-kynurenine via ozonolysis.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788020
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