Title of article :
Asymmetric synthesis of cis-(−)-(2R4S)-4-(phosphonomethyl)-2-piperidinecarboxylic acid, a potent NMDA receptor antagonist
Author/Authors :
Jerry W. Skiles، نويسنده , , Peter P. Giannousis، نويسنده , , Kevin R. Fales، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
The asymmetric synthesis of cis-(−)-(2R4S)-4-(phosphononomethyl)-2-piperidinecarboxylic acid (1), a potent and specific NMDA receptor antagonist, via an olefin-iminium cyclization is described.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
