Author/Authors :
Jeffrey J. Ares، نويسنده , , Pamela E. Outt، نويسنده , , Jared L. Randall، نويسنده , , Jeffrey N. Johnston، نويسنده , , Peter D. Murray، نويسنده , , Linda M. OʹBrien، نويسنده , , Pamela S. Weisshaar، نويسنده , , Beth L. Ems، نويسنده ,
Abstract :
Several analogs of the gastroprotective molecule flavone have been synthesized and evaluated for gastroprotective activity. A C2–C3 double bond and an intact C ring appear necessary for optimum activity. Activity can be retained by replacing the 2-phenyl substituent with other groups but is eliminated when this ring is moved from the 2- to the 3-position.
