Title of article :
Synthesis and anti-HIV activity of dihydroisoxazole 6-chloropurine and adenine
Author/Authors :
Yuejun Xiang، نويسنده , , Jie Chen، نويسنده , , Raymond F. Schinazi، نويسنده , , Kang Zhao، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
Dihydroisoxazole 6-chloropurine and adenine were efficiently prepared via 1,3-dipolar cycloaddition reaction of a nitrile oxide with vinyl 6-chloropurine, and found to be moderately effective against HIV-1 in acutely infected primary human lymphocytes.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters