Title of article :
Synthesis, biological activity and quantitative structure-activity relationships of N-substituted-3,4-dihydro-2H-1-benzopyran derivatives
Author/Authors :
C. Marot، نويسنده , , C. Comoy، نويسنده , , M. C. Viaud، نويسنده , , M. C. Rettori، نويسنده , , B. Pfeiffer، نويسنده , , L. Morin-Allory، نويسنده , , G. Guillaumet، نويسنده ,
Abstract :
Synthesis of N-substituted-3,4-dihydro-2H-1-benzopyran derivatives which have a potential affinity for the 5-HT1A receptor is reported. The comparison between the experimental values of binding and the prediction of Q.S.A.R. studies is described.