Title of article
A convenient procedure for the solution phase preparation of 2-aminothiazole combinatorial libraries
Author/Authors
Nicholas Bailey، نويسنده , , Anthony W. Dean، نويسنده , , Duncan B. Judd، نويسنده , , David Middlemiss، نويسنده , , Richard Storer، نويسنده , , Stephen P. Watson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
1409
To page
1414
Abstract
A convenient procedure for the solution phase preparation of 2-aminothiazole combinatorial libraries is described. The library preparation is simple, practical, and effective, generating compounds based around a known pharmacophore in high yield and purity. Furthermore, the procedure tolerates a diverse range of functionality in its substrates and is notable in allowing the preparation of compounds containing both free acids and bases without recourse to protection.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788128
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