Title of article
Synthesis and evaluation of 2-(biphenylmethyl)glutaric acid amide derivatives as neutral endopeptidase inhibitors.
Author/Authors
Hideyuki Kanno، نويسنده , , Ken Osanai، نويسنده , , Tatsuya Nishi، نويسنده , , Minoru Iino، نويسنده , , Shin-ichi Katakura، نويسنده , , Taketoshi Furugohri، نويسنده , , Yoshifumi Watanabe، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
1487
To page
1490
Abstract
A series of 2-(biphenylmethyl)glutaric acid amide derivatives were synthesized and evaluated for NEP inhibitory activity. The mode of inhibitor-enzyme interactions of the most potent compound 3a, with a thiazolylacetic acid group at the P2ʹ position, was evaluated by a computer analysis.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788144
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