Remarkable hydrolysis of phosphodiester by neutral lanthanide(III) DO3A complexes

The hydrolysis of the 4-nitrophenyl phosphate ester of propylene glycol (HPNP) is catalyzed by neutral lanthanide(III) DO3A complexes. Hydrolysis experiments with complexes of modified ligands where the metal complex was positively charged did not yield in a significant increase of the rate constant.