Title of article :
Synthesis of water soluble prodrug of DMP323
Author/Authors :
Prabhakar K. Jadhav، نويسنده , , Francis J. Woerner، نويسنده , , Bruce J. Aungst، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
A water soluble bisphosphate prodrug of DMP323 was synthesized from DMP323. Pharmacokinetic studies of the prodrug indicate that it is orally absorbed as the parent drug, after hydrolysis of the phosphate ester in the gastrointestinal tract.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters