Title of article
Synthesis and pharmacological profile of new 1,3-disubstituted cyclohexanes as leukotriene B4 receptor antagonists
Author/Authors
J. M. Poudrel، نويسنده , , P. Hullot، نويسنده , , J. P. Vidal، نويسنده , , J. P. Girard، نويسنده , , J. C. Rossi، نويسنده , , A. Muller، نويسنده , , C. Bonne، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
2349
To page
2354
Abstract
In the course of developing stable leukotriene B4 antagonists, we synthesized a novel non aromatic series of compounds containing a 1,3-disubstituted cyclohexane ring in place of the conjugated double bonds of the natural eicosanoid. The Structure-Activity Relationship (SAR) studies leading to the identification of the acid are described.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788354
Link To Document