Title of article
Application of the Heck reaction in the synthesis of truncated naphthoic acid retinoids
Author/Authors
Kuo-Long Yu، نويسنده , , Simon Chen، نويسنده , , Jacek Ostrowski، نويسنده , , Kenneth M. Tramposch، نويسنده , , Peter R. Reczek، نويسنده , , Muzammil M. Mansuri، نويسنده , , John E. Starrett Jr، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
2859
To page
2864
Abstract
A series of truncated naphthoic acid retinoids have been prepared using the Heck reaction. These retinoids were evaluated in the RAR transactivation assay in vitro and in the utriculi reduction assay in vivo. It has been found that the naphthalene ring of the retinoids is crucial for their retinoid activity and receptor selectivity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788454
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