Title of article :
Inhibition of calpain by peptidyl heterocycles
Author/Authors :
Ming Tao، نويسنده , , Ron Bihovsky، نويسنده , , James C. Kauer، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
Dipeptidyl and tripeptidyl heterocycles designed to mimic peptide ketoanides and ketoacids were prepared and evaluated in vitro as inhibitors of human calpain I. Boc-Leu-Leu-imidazole (12) inhibited calpain I at low micromolar concentrations.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
