Title of article :
6-(4-Phenyl-benzyloxy-methyl) guvacine. Synthesis, GABA uptake inhibitor and muscarinic properties
Author/Authors :
Philippe Bisel، نويسنده , , Jean Pierre Gies، نويسنده , , Gilbert Schlewer، نويسنده , , Camille G. Wermuth، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
6-(4-Phenyl-benzyloxy-methyl) guvacine was synthesized. Surprisingly the compound was devoid of the γ-aminobutyric acid (GABA) uptake inhibitory activity of its parent compound guvacine, but instead showed affinities for the muscarinic M1 and M2 receptors.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
