Title of article :
3-Amino-1,2-benzisoxazoles: A new family of potent inhibitors of LTB4 binding to the human neutrophils
Author/Authors :
Hongsuk Suh، نويسنده , , Soo-Jeong Jeong، نويسنده , , Yong Nam Han، نويسنده , , Hwa-Jin Lee، نويسنده , , Jae-Ha Ryu، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Abstract :
A new family of 3-amino-1,2-benzisoxazoles was designed and synthesized to be a potent inhibitors of LTB4 binding to the human neutrophils. HS-1141 appears to be one of the strongest inhibitors of LTB4 binding reported so far (IC50=7nM).
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
