Molecular connectivity to find β-blockers with low toxicity
Author/Authors :
R. Garc?a-Domenech، نويسنده , , C. de Gregorio Alapont، نويسنده , , J. V. de Juli?n-Ortiz، نويسنده , , J. G?lvez، نويسنده , , L. Popa، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Pages :
6
From page :
567
To page :
572
Abstract :
Molecular connectivity has been used to find new β-blocker drugs using linear discriminant analysis and connectivity functions with different topological descriptors. Among the selected compounds stands out the probucol and the β-carotene. Both of them interact with β adrenoceptors.
