Hybrid anthracyclines by a genetically engineered Streptomyces galilaeus mutant
Author/Authors :
Tero Kunnari، نويسنده , , Jarmo Niemi، نويسنده , , Kristiina Ylihonko، نويسنده , , Pekka M?nts?l?، نويسنده , , Juha Hakala، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Pages :
2
From page :
725
To page :
726
Abstract :
A Streptomyces galilaeus mutant carrying genes transfered from S. purpurascens is reported to produce two hybrid anthracyclines. This study demonstrates the possibility of producing hybrid anthracyclines in a combinatorial way by genetic engineering of anthracycline producing strains.