Author/Authors :
Omar Parve، نويسنده , , Imre Vallikivi، نويسنده , , Lilja Lahe، نويسنده , , Andrus Metsala، نويسنده , , Ulo Lille، نويسنده , , Vello T?ugu، نويسنده , , Heiki Vija، نويسنده , , T?nis Pehk، نويسنده ,
Abstract :
The esters derived from 2-exo-bromo-3-endo-hydroxybicyclo[3.2.0]heptan-6-one were treated with Lipolase under hydrolytic conditions in supercritical carbon dioxide (SCCO2). All the esters tested gave access to optically active material (e.e. 50–90%). The esters with an additional keto or hydroxy group were hydrolysed to 35–40% conversion while nonpolar lipophilic substrates gave poor conversions (3–5%) under the same conditions.
