Author/Authors :
Byoung-Mog Kwon، نويسنده , , Seungho Lee ، نويسنده , , Kyung Sook Kim، نويسنده , , Ihn-Rhan Lee، نويسنده , , Un-Chul Lee، نويسنده , , Su-Hyung Hong، نويسنده , , Song-Hae Bok، نويسنده ,
Abstract :
Rhombenone, a new dammarane analogue containing an 25-oxo, which inhibits farnesyl protein transferase (FPTase), was isolated from the leaves of Hedera rhombea Bean. Additional related dammaranes were also evaluated for FPTase inhibition.