Title of article :
An efficient preparation of the potent and selective pseudopeptide thrombin inhibitor, inogatran
Author/Authors :
Patrice Préville، نويسنده , , John X. He، نويسنده , , Micheline Tarazi، نويسنده , , M. Arshad Siddiqui، نويسنده , , Wayne L. Cody، نويسنده , , Annette M. Doherty، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Pages :
4
From page :
1563
To page :
1566
Abstract :
Inogatran is an effective and selective pseudopeptide inhibitor of thrombin that has been shown to be efficacious in a series of in vitro and in vivo models of thrombosis. Herein, we report an efficient and convergent chemical synthesis of Inogatran that is amenable to the preparation of multiple gram quantities.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1997
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
788810
Link To Document :
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