Synthesis and structure-activity relationship of C-3 benzoyloxymethyl cephalosporins exhibiting anti-MRSA activities
Author/Authors :
Oak K. Kim، نويسنده , , Yasutsugu Ueda، نويسنده , , Muzammil M. Mansuri، نويسنده , , John W. Russell، نويسنده , , Valerie W. Bidwell، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Pages :
6
From page :
1945
To page :
1950
Abstract :
A series of cephalosporins bearing C-3 benzoyloxymethyl groups were prepared and evaluated for their anti-MRSA activity and plasma stability. They exhibit excellent in vitro activity (MIC = 0.06 2 μg/mL) against MRSA and excellent stability in human plasma.
