Title of article :
Design, syntheses and potentiating activities against methicillin resistant Staphylococcus aureus of cyclic analogs of LY301621
Author/Authors :
Clark N. Eid، نويسنده , , Thalia I. Nicas، نويسنده , , Deborah L. Mullen، نويسنده , , Richard J. Loncharich، نويسنده , , Jonathan W. Paschal، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Abstract :
Previous SAR studies of the diastereomers of LY301621 suggested the importance of a β-turn conformation for biological activity. In the present study, cyclic analogs were designed and synthesized that possess Type II and IIʹ β-turns. Their biological activity will be discussed
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
