Title of article
Hemisynthesis of rhazinilam analogues: structure - activity relationships on tubulin-microtubule system
Author/Authors
Bruno David، نويسنده , , Thierry Sévenet، نويسنده , , Odile Thoison، نويسنده , , Khalijah Awang، نويسنده , , Mary Païs، نويسنده , , Michel Wright، نويسنده , , Daniel Guénard، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
2155
To page
2158
Abstract
Semi-synthesis of derivatives of rhazinilam, an antitubulin compound, delineated some molecular features necessary for biological activity. In the course of this study, the formation of rhazinilam from 1,2-didehydroaspidospermidine is reexamined and a new mechanism is proposed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788924
Link To Document