Author/Authors :
Larry C. Blaszczak، نويسنده , , Clark N. Eid، نويسنده , , Jane Flokowitsch، نويسنده , , G. Stuart Gregory، نويسنده , , Stephen A. Hitchcock، نويسنده , , George W. Huffman، نويسنده , , Daniel R. Mayhugh، نويسنده , , Michael J. Nesler، نويسنده , , David A. Preston، نويسنده , , Mohammad Zia-Ebrahimi، نويسنده ,
Abstract :
The synthesis of a series of 3-thiosubstituted carbacephem derivatives is described. The compounds were assayed against penicillin susceptible, intermediate and resistant strains of Streptococcus pneumoniae. Several analogs displayed potent in vitro activity against these organisms.
