The inhibition of glutamate racemase by

We report that is a competitive inhibitor of glutamate racemase (KI = 56 μM). The compound acts as an alternate substrate and is converted into α-ketoglutarate and ammonia (KM = 57 μM, kcat/KM = 3.2 × 103M−1sec−1). An imine intermediate is likely the species causing the inhibition. is a weak inhibitor and is slowly converted to α-ketoglutarate (kcat/KM = 30 M−1sec−1).