Solid-phase synthesis of hybrid thiazolidinedione-fatty acid PPARγ ligands
Author/Authors :
Nicholas C. O. Tomkinson، نويسنده , , Andrea M. Sefler، نويسنده , , Kelli D. Plunket، نويسنده , , Steven G. Blanchard، نويسنده , , Derek J. Parks، نويسنده , , Timothy M. Willson and Shawn P. Williams، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Pages :
6
From page :
2491
To page :
2496
Abstract :
A library of thiazolidinedione-fatty acid hybrid molecules was designed to probe the relationship between natural and synthetic PPAR ligands. Solid-phase synthesis of the library led to the identification of several high affinity PPARγ ligands.
