• Title of article

    Targeting DNA topoisomerase II with podophyllotoxin aza-analogue

  • Author/Authors

    Akira Iida، نويسنده , , Masahiro Kano، نويسنده , , Yoshihiro Kubota، نويسنده , , Kenji Koga and Harutoshi Takeo، نويسنده , , Kiyoshi Tomioka، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    2
  • From page
    2565
  • To page
    2566
  • Abstract
    Oxidation of a cytotoxic podophyllotoxin aza-analogue 2 into the quinone 3succeeded in acquiring DNA topoisomerase II inhibitory activity at a concentration of 25 μM due to stabilization of the cleavable complex.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789003