Title of article
Resolution and biological activities of optical isomers of 1,4-diethyl-3,6-epidithiopiperazine-2,5-dione
Author/Authors
Alanna M. Hurne، نويسنده , , Melkamu Zeleke and Jamie Simpson، نويسنده , , Paul Waring، نويسنده , , Christina L. L. Chai، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
2645
To page
2650
Abstract
Epipolythiopiperazine-2,5-diones (ETPs) are an important class of biologically active fungal metabolites. We have successfully synthesised and resolved racemic 1,4-diethyl-3,6-epidithiopiperazine-2,5-dione using chiral HPLC. The biological activities of the enantiomers were investigated to determine the correlation between biological activity and chirality at the bridgehead carbons.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789019
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