Author/Authors :
Stephen Hanessian، نويسنده , , Gurijala V. Reddy، نويسنده , , Hoan K. Huynh، نويسنده , , Jingwen Pan، نويسنده , , Silvana Pedatella، نويسنده , , Beat Ernst، نويسنده , , Hartmuth C. Kolb، نويسنده ,
Abstract :
The synthesis of sialyl Lewisx mimetic anologs in which the -glucosamine, -galactose, and sialic acid residues are replaced individually with appropriate glycomimetics is described. A computational model for predicting bioactive conformations was tested.