Synthesis and structure-activity relationship of C-3 quaternary ammonium cephalosporins exhibiting anti-MRSA activities
Author/Authors :
Oak K. Kim، نويسنده , , Thomas W. Hudyma، نويسنده , , John D. Matiskella، نويسنده , , Yasutsugu Ueda، نويسنده , , Joanne J. Bronson، نويسنده , , Muzammil M. Mansuri، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Pages :
6
From page :
2753
To page :
2758
Abstract :
A series of cephalosporins bearing C-3 quaternary ammonium groups were prepared and evaluated for their anti-MRSA activity. They exhibit good to excellent in vitro activity (MICs = 1−8 μg/mL) against MRSA.
