Synthesis of (alkoxycarbonyloxy)methyl, (acyloxy)methyl and (oxodioxolenyl)methyl carbamates as bioreversible prodrug moieties for amines

Synthesis of (alkoxycarbonyloxy)methyl carbamates of secondary amines was developed, and it was extended to (acyloxy)methylation of benzylmethylamine and (oxodioxolenyl)methylation of benzylamine, benzylmethylamine, and L-phenylalanine.