• Title of article

    5-aminomethylquinoxaline-2,3-diones. Part II: N-aryl derivatives as novel NMDA/glycine and AMPA antagonists

  • Author/Authors

    Yves P. Auberson، نويسنده , , Pierre Acklin، نويسنده , , Hans Allgeier، نويسنده , , Michel Biollaz، نويسنده , , Serge Bischoff، نويسنده , , Silvio Ofner، نويسنده , , Siem J. Veenstra، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    4
  • From page
    71
  • To page
    74
  • Abstract
    Potent antagonists at the glycine-binding site of NMDA receptors, as well as dual antagonists acting also at AMPA receptors have been identified in a series of 5-arylaminomethylquinoxaline-2,3-diones. A study of the structure-activity relationship of these compounds is reported here.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789181