Title of article :
Novel antiproliferative falcarindiol furanocoumarin ethers from the root of Angelica japonica
Author/Authors :
Kazuhiro Furumi، نويسنده , , Toshihiro Fujioka، نويسنده , , Hiroko Fujii، نويسنده , , Hikaru Okabe، نويسنده , , Yukitaka Nakano، نويسنده , , Hisashi Matsunaga، نويسنده , , Mitsuo Katano، نويسنده , , Masato Mori، نويسنده , , Kunihide Mihashi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Abstract :
Four novel antiproliferative furanocoumarin ethers of falcarindiol, named japoangelols A (8.5), B (7.2), C (7.4), and D (8.4), were isolated from the root of Angelica japonica together with panaxynol (0.3), falcarindiol (3.2), (9Z)-1,9-heptadecadiene-4,6-diyne-3,8,11-triol (2.2), and 8-acetoxyfalcarinol (3.2). Structures were established from the spectroscopic evidence, and the inhibitory activities (ED50, μg/ml, shown in the parentheses) were evaluated using the MTT assay
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
