Title of article
Design and synthesis of a water-soluble taxol analogue : Taxol-sialyl conjugate
Author/Authors
Takashi Takahashi، نويسنده , , Hirokazu Tsukamoto، نويسنده , , Haruo Yamada، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
113
To page
116
Abstract
Glycosidation, using the methylthio derivative of N-acetylneuraminic acid 3, of linker alcohol 4 in DME with “long-range participation” produced the α-glycosyl linkage with high stereoselectivity. The α-linked sialic acid 2 was introduced in taxol without protection of the alcohol functionality in sialic acid.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789189
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