Title of article
Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids
Author/Authors
Julian Adams، نويسنده , , Mark Behnke، نويسنده , , Shaowu Chen، نويسنده , , Amy A. Cruickshank، نويسنده , , Lawrence R. Dick، نويسنده , , Louis Grenier، نويسنده , , Janice M. Klunder، نويسنده , , Yu-Ting Ma، نويسنده , , Louis Plamondon، نويسنده , , Ross L. ، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
333
To page
338
Abstract
Potent and selective dipeptidyl boronic acid proteasome inhibitors are described. As compared to peptidyl aldehyde compounds, boronic acids in this series display dramatically enhanced potency. Compounds such as 15 are promising new therapeutics for treatment of cancer and inflammatory diseases.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789236
Link To Document