Functionalized 1,3-teraryls as a new class of hepatoprotectants: Part V

Functionalized 1,3-teraryls, synthesized through ring transformation of 6-aryl-3-carbomethoxy-4-methylthio-2H-pyran-2-one from arylketone have been screened for their hepatoprotective activity and some of them have demonstrated significant protection in animal model.