Author/Authors :
Braj B. Lohray، نويسنده , , S. Baskaran and T Pradeep ، نويسنده , , Bonthu Srinivasa Rao، نويسنده , , B. Mallesham، نويسنده , , K. S. N. Bharath، نويسنده , , B. Yadi Reddy، نويسنده , , S. VENKATESWARLU & J. C. KATYAL، نويسنده , , Ashok K. Sadhukhan، نويسنده , , M. Sitaram Kumar، نويسنده , , Hemant M. Sarnaik، نويسنده ,
Abstract :
Several 7-(3R,4R-N,N′-dialkyl diaminopyrrolidinyl)-substituted quinolones were synthesized and evaluated for antibacterial activities. 5-Amino-7-(3R,4R-N,N′-dimethyldiamino-6,8-difluoro-1,4-dihydro-1-cyclopropyl-4-oxoquinoline-3-carboxylic acid was found to have potent antibacterial activity against gram + ve organïsms.
