Title of article
Discovery of a new cyclooxygenase-2 lead compound through 3-D database searching and combinatorial chemistry
Author/Authors
Kent D. Stewart، نويسنده , , Stefan Loren، نويسنده , , Lisa Frey، نويسنده , , Ellen Otis، نويسنده , , Vered Klinghofer، نويسنده , , Keren I. Hulkower، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
529
To page
534
Abstract
Using a combination of computational and combinatorial chemistry methodologies, a phenothiazine compound was discovered that is a selective inhibitor of cyclooxygenase-2 and serves as a lead compound for a potentially novel series of anti-inflammatory compounds.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789275
Link To Document