Title of article
Use of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide and isothiazolidin-3-one 1,1 dioxide scaffolds in the design of potent inhibitors of serine proteinases
Author/Authors
Rongze Kuang، نويسنده , , Radhika Venkataraman، نويسنده , , Sumei Ruan، نويسنده , , William C. Groutas، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
539
To page
544
Abstract
The attachment of a phosphate leaving group to the 1,2,5-thiadiazolidin-3-one 1,1 dioxide and isothiazolidin-3-one 1,1 dioxide scaffolds was found to yield highly potent, time-dependent inhibitors of human leukocyte elastase (HLE).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789277
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