Title of article
An approach to use an unusual adenosine transporter to selectively deliver polyamine analogues to trypanosomes
Author/Authors
Ching-Kim Tye، نويسنده , , Ganasan Kasinathan، نويسنده , , MICHAEL P. BARRETT، نويسنده , , Reto Brun، نويسنده , , Valerie E. Doyle، نويسنده , , Alan H. Fairlamb، نويسنده , , Richard Weaver، نويسنده , , Ian H. Gilbert، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
811
To page
816
Abstract
In this paper we describe an approach to selectively deliver compounds to trypanosomes using an adenosine transporter which is unique to the trypanosome. Various polyamine analogues have been attached to known substrates of this adenosine transporter. The compounds prepared interact specifically with the adenosine transporter, some with a similar efficiency to berenil, a known substrate.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789328
Link To Document